
Singderm Universal is a sterile, biodegradable, nonpyrogenic, viscoelastic, clear, colorless, homogenized gel implant. Mono-phasic Dermal Filler consists of modified hyaluronic acid (HA) produced by bacteria, formulated to a concentration of 24 mg/ml and 0.3% lidocaine in a physiologic buffer. Indicated for injection into the mid to deep dermis or subcutaneous for correction of mid or deep depressions of the skin, as well as for correcting age-related volume deficit.
Singderm® is presented in a graduated, pre-filled, disposable syringe. Each box contains one syringe, an instruction leaflet and a set of labels in order to ensure traceability. The contents of the Singderm® syringe are sterilized by moist heat. If presense, the needles are sterilized by radiation or ethylene oxide.

| Singderm® | |||
| Indication | Indicated for facial tissue augmentation by injection into areas in which restoration is required, including reconstructive treatment of volume loss as well as for facial morphological asymmetry. | ||
| Injection Layer | Mid to deep dermis or subcutaneous | ||
| Duration | Up to 12 months | ||
| HA Concentration | 24mg/mL | ||
| HA Raw Material | Non Animal, produced by Streptococcus species of bacteria | ||
| Lidocaine | 0.3% | ||
| Water affinity | ●●◌◌◌ | ||
| G' (Hardness) | ●●●◌◌ | ||
| Cohesivity | ●●●●◌ | ||
| Specification | 1 mL | 2 mL | 10 mL |
| Enclosed Needles | 2*27G | 2*26G | NA |
| Certificate | NMPA CE MHRA TFDA Anvisa | ||
| Used in | Over 30 Countries | ||
Singderm Universal Advantages
World-class HA Raw Material
High Purity: this non-animal hyaluronic acid is produced through bacterial fermentation to ensure high purity.
High Quality: sourced from internationally advanced biotechnology. Selected high-quality hyaluronic acid raw materials.
High Assurance: product quality strictly adheres to the high standards of EP or JP and has passed high-quality clinical
Painless Comfort Technology
Contain 0.3% LIDOCAINE, significantly reduce pain and improve result
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High Concentration of Effective HA
| Company | Singclean® | Company M | Company M | Company B | Company G |
| Brand | Singderm® | Brand B | Brand B | Brand C | Brand M |
| HA Content(mg/ml) | 24 | 22.5 | 26 | 20 | 24 |
| Cross-linked HA | 21.6(90%) | 8.325(37%) | 17.55(67.5%) | 16.4(82%) | 19(79%) |
| non cross-linked HA | 2.4(10%) | 14.175(63%) | 8.45(32.5%) | 3.6(18%) | 5(21%) |
High Concentration of Cross-linked HA to achieve good lifting effect and last longer.
Source: NMPA public information
Safety Assurance
| Safety Test Report | ||
| Test Items | Standard | Results of Testing |
| Protein Content | ≤0.1% | Qualified(0.04%) |
| Crosslinking Agent Residue | ≤2.0μg/g | Not detected |
| Sterility | Should be sterile | Sterile |
| Heavy Metal | ≤5μg/g | Conformity |
| Bacterial endotoxin | <0.5EU/mL | Conformity |
| Hemolysis | No hemolysis ring | Conformity |
Source: Singderm® Modified Sodium Hyaluronate Gel for injection Test Report, Report Number: BGI2510001
Clinical Effectiveness Rate
Time after injection(month) | 3 Month | 6 Month | 12 Month |
Effectiveness rate | 96.50% | 94.00% | 92.70% |
•The efficacy rate is measured by wrinkle severity rating scale(WSRS) from baseline.
•This clinical trial being a self-controlled study was performed in 3 top hospitals, 100 subjects participated.
Notably, Singderm® effectiveness rate at 12 months of 92.7% surpasses the 83% effectiveness rate reported for a leading comparator (Product J) at the same time point, indicating superior long-term efficacy.
Source 1: Clinical trial report on the efficacy and safety evaluation of Singderm®
Source 2: Product J IFU
High-standard Production Process
28,000 ㎡ state-of-the-art intelligent manufacturing base features fully automated production lines
Operating within Class 10,000 and Class 100 cleanrooms, the entire process adheres to international standards.
Utilize USA polymer cellulose dialysis membranes to efficiently remove residual cross-linking agents and impurities.
German Optima aseptic filling technology ensures absolute protection against contamination.
Sweden Getinge sterilizer, achieving a terminal Sterility Assurance Level (SAL) of 10⁻⁶.
Shelf life is 2 years, Store at 2°C to 30°C, DO NOT FREEZE.
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Singderm® has been honored with multiple prestigious awards, reinforcing its position as an industry leader in China. Notable recognitions include:
•HA Filler Innovative Brand
•Most Loved HA Filler Brand
•Brand Voice Excellence Award
•Influential Brand of the Year
Committed to promoting high-quality development of global medical aesthetics
With 23 years of expertise in medical aesthetics R&D and manufacturing, Singclean is now one of the leading forces in the industry.
50+: Obtained local registration in over 50 countries
80+: Sales channels cover 80+ countries and regions
10%: Over 10% of revenue is spent on R&D each year
330: Have more than 330 global OEM ODM OBL partners
World-Class Manufacturing
Equipped with Asia's largest automated HA gel production facility, Singclean innovations are engineered to rigorous international GMP standards for unmatched quality and consistency.
Successful Brand Portfolio
Trusted by practitioners worldwide, Singderm, Singfiller and SKformula represent over 5 million syringes of proven clinical performance and physician confidence.
Unveiling the Next Generation of Aesthetics
Expanding beyond HA, Singclean introduces a rich portfolio of advanced aesthetic solutions — including biostimulators (PLLA, CaHA hybrid filler), PDRN skinboosters, post-treatment care, and natural skincare — designed to meet every clinical need.
Q: What is Singderm® dermal filler?
A: Singderm® dermal filler is made of 24.0mg/ml concentration cross-linked and 0.3% lidocaine, the HA is from microbial fermentation. It supplies good facial injection effects and painless injection experience.
Q: What are the advantages of Singderm® dermal filler?
A: No animal ingredients, Long lasting results Biodegradable, Good facial injection effects and Painless injection experience.
Q: Are you trading company or manufacturer?
A: We produce our own brand products in our own factory.
Q: How long is your delivery time?
A: Your order can be shipped within one day after you made the payment.
DHL or EMS delivery time: 3-7 days from China to other countries around the world.
Q: Do you provide samples?
A: Our MOQ is 10pcs. For your first order, you can order samples for checking quality.
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No. 125(E), 10th Street, Hangzhou Qiantang Area, Zhejiang, China