SKformula Sodium Hyaluronate Solution for Mesotherapy

SKformula Sodium Hyaluronate Solution for Mesotherapy

SKformula is a visco-elastic solution designed to replenish hyaluronic acid and revitalize skin quality. Its primary ingredient is pure, non-crosslinked Hyaluronic Acid (HA), specifically at a concentration of 10 mg/mL, sourced from biofermentation for high purity and compatibility, acting as a skin booster.

For those trying meso injections for the first time, especially individuals with sensitive skin, priority should be given to pure, high-safety products that feature simple ingredients and do not burden the skin.


Details of SKformula Sodium Hyaluronate Solution for Mesotherapy

SKformula Sodium Hyaluronate Solution for Mesotherapy
SKformula Sodium Hyaluronate Solution for Mesotherapy

Indications

It is used in medical institutions and is intended for injection into the dermal layer of theskin (e.g., face, neck, hands, etc.). It can significantly boosts hydration, enhance skin elasticity of sagging skin, improve dull skin tone, and smooth away fine lines.

 

Specification

10mg/mL: 0.5mL, 1.0mL, 1.5mL, 2.0mL, 2.5mL, 3.0mL

 

Core Ingredients

10 mg/mL Hyaluronic Acid (non-crosslinked)

 

Suitable For

People with dry, dehydrated skin, or fine lines and wrinkles.

 

Function

Hydrate, plump, and rejuvenate the skin by restoring natural moisture and improving elasticity.

 

Mode Of Action

After high-molecular-weight hyaluronic acid is injected into the dermal layer of the skin, the carboxyl groups and other polar groups in hyaluronic acid molecules can form hydrogen bonds with water to bind a large amount of moisture.

This enhances the skin's hydration capacity, increases skin volume to fill superficial wrinkles, and improves skin moisture content from the inside out under the  action of aquaporins—significantly boosting the moisture content of the stratum corneum, reducing fine lines, and enhancing skin elasticity.

Meanwhile, sodium hyaluronate can also stimulate the proliferation of fibroblasts and promote the synthesis of collagen, which further enhances skin elasticity and helps restore firmness to sagging skin.


skin-booster-01.jpg 

 

Clinical Data

A prospective, multi-center, randomized, placebo-controlled, assessor-blinded, and superiority clinical trial design was conducted.

A total of 484 subjects were enrolled, with a 3-month follow-up period. The subjects were adults in need of temporary improvement in facial skin condition (such as dry skin and dull skin tone). The test group received injections of SKformula at week 0, 4, and 8, with each dose ranging from 3 to 6 mL.

Summary of Clinical Trial Results and Conclusions: In terms of efficacy evaluation, the proportion of patients with sustained skin improvement for 4 weeks was 92.6%, and for 3 months was 89.1%; the proportion of patients with sustained Global Aesthetic Improvement Scale (GAIS) effect for 4 weeks was 93.9%, and for 3 months was 89.5%.

No adverse events occurred.


 

Conclusion

Based on the comparison of the two sets of data, it can be concluded that the skin moisture and elasticity levels of the test group showed a steady increasing trend at weeks 4, 8, and 12 after continuous use of the SKformula product. Moreover, the degree of improvement at each time point was significantly better than that of the blank control group, indicating that the product delivers clear and sustained effects in long-term moisturizing and enhancing skin elasticity.

 

Advantages

World Top HA Raw material

Using exceptionally pure, Kewpie Corporation non-animal Hyaluronic Acid, with strict quality control and Japanese Pharmacopoeia compliance, this formulation deeply moisturizes the skin while smoothing and refining its texture.

 

Long-lasting Hydration with High-Molecular-Weight HA

By utilizing high-molecular-weight sodium hyaluronate (approximately 2 million Daltons), the product ensures superior hydrating and moisture-locking performance, offering over 3 months of plumping and revitalization effects.

 

High Safety Profile & Pyrogen-Free

With significantly reduced levels of endotoxins and foreign proteins, plus a streamlined ingredient composition, it greatly minimizes the risk of adverse reactions and supports greater skin compatibility.

 

Versatile Usage

HA Mesotherapy's versatility shines as it deeply hydrates and boosts collagen, making it a perfect

partner with ingredients like vitamins, PDRN, collagen stimulators (like PDLLA) to enhance overall rejuvenation.

 

Injection Sites

Face

Neck

Decollete area

Backs of hands

Peri-orbital area (eye contour)


meso-injection.jpg 

 

Direction For Use

It should be injected into healthy disinfected skin with no sign of inflammation.

This implant is designed to be injected into the dermis by a licensed medical practitioner using the appropriate technique.

This treatment can be carried out manually using a 32G needle or in association with a device like mesotherapy injector.

Treatment protocol consists in 3 sessions spaced out between 4 weeks.

 

Duration

Optimal results lasting 3+ months.

 

Suggested HA-Based Combination Therapy

Tailor the protocol to skin type and concerns—more products don't always mean better results. Start with a basic HA solution, then add only 1-2 targeted agents.

The typical dose is 3–6 mL per session (5 mL is common), adjusted individually for skin area, thickness, and product specifics. Always blend products proportionally based on their concentrations.

 

Examples of Combination Protocols:

HA + Regenerative/Collagen Booster

Lifts, firms, reduces fine lines

 

HA + Vitamin C + Glutathione

Antioxidant brightening

 

HA + PDRN/PN

Boosts metabolism, anti-inflammatory

 

HA + Botulinum Toxin

Reduces fine lines, pores, oil, and acne


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